Molecule profile · Module 4
CJC-1295 without DAC — evidence and research limits
This label describes the research context of this profile, not a product-by-product approval determination. It does not mean every use of the molecule lacks approval. Read the existing evidence details and regulatory context for the specific preparation, indication and jurisdiction; no new approval is inferred.
MOLECULE PROFILE
- Evidence summary
- Investigational — profile context
- Teichman and colleagues studied long-acting CJC-1295 in healthy adults and measured GH and IGF-1 responses. The trial does not validate products labeled 'without DAC,' mixtures, or claims of improved sleep, strength, or longevity. Verify the actual sequence and conjugation rather than assuming a marketing name identifies the studied intervention. The interpretation is specific to the studied molecule, formulation, route, population, and endpoint. Reported commercial regimens are not validated by a study of a different product or outcome.
- Regulatory status varies by jurisdiction
- The academic source does not establish a current authorization for every preparation sold under this name. Product identity, formulation, indication, jurisdiction, and current official labeling must be checked separately. A discussion of compounding or an advisory meeting is not a product approval.
Educational information for healthcare professionals and the general public. Not individual medical advice, diagnosis, treatment, or a recommendation to use a compound.
Identity and mechanism
Products described as CJC-1295 without DAC are discussed in relation to growth hormone-releasing hormone signaling. The name needs special scrutiny: a modified growth hormone-releasing factor sold without DAC cannot be treated as the same intervention as the long-acting CJC-1295 investigated in the cited human study. Molecular characterization precedes any comparison of exposure or hormone response.
What the evidence supports
Teichman and colleagues studied long-acting CJC-1295 in healthy adults and measured GH and IGF-1 responses. The trial does not validate products labeled 'without DAC,' mixtures, or claims of improved sleep, strength, or longevity. Verify the actual sequence and conjugation rather than assuming a marketing name identifies the studied intervention.
The interpretation is specific to the studied molecule, formulation, route, population, and endpoint. Reported commercial regimens are not validated by a study of a different product or outcome.
Regulatory context
The academic source does not establish a current authorization for every preparation sold under this name. Product identity, formulation, indication, jurisdiction, and current official labeling must be checked separately. A discussion of compounding or an advisory meeting is not a product approval.
Safety and uncertainty
Identify modification and product. The hormonal response does not allow for the transfer of event rates between formulations or guarantee the safety of combinations. Human safety cannot be inferred from a cell result, a product name, or lack of events in a small report. These educational adaptations do not provide an administration protocol.
Sport and anti-doping status
The WADA 2026 Prohibited List names CJC-1293 and CJC-1295 among growth hormone-releasing hormone analogues in section S2.2.4, prohibited at all times; the section also covers substances with similar chemical structure or similar biological effect, so a “without DAC” label does not remove the question. This is an anti-doping classification, separate from clinical evidence, product quality and regulatory approval. Medical supervision, a prescription or an approved indication does not by itself permit use in sport; any exemption for a documented medical condition is a separate decision by the competent anti-doping organization. The List is revised each year, so check the List in force on the relevant date.
Continue learning
Explore Module 4 in PEPTIDE Academy for the full evidence discussion.
References
Bibliographic sources shown for transparency. Citation verification pending; no citation is marked verified.
- Teichman SL, Neale A, Lawrence B, et al. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. 2006;91(3):799-805. DOI: 10.1210/jc.2005-1536. PMID: 16352683.DOI 10.1210/jc.2005-1536 · PMID 16352683
- Liu H, Bravata DM, Olkin I, et al. Systematic review: the safety and efficacy of growth hormone in the healthy elderly. Ann Intern Med. 2007;146(2):104-15. DOI: 10.7326/0003-4819-146-2-200701160-00005. PMID: 17227934.DOI 10.7326/0003-4819-146-2-200701160-00005 · PMID 17227934
- World Anti-Doping Agency. International Standard: Prohibited List 2026 (in effect from 1 January 2026). Checked 19 October 2026.
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