MIC / Lipo-C with B12

Components

• Methionine
• Inositol
• Choline
• Vitamin B12
• Other ingredients vary

Community claim

Metabolism or energy claims.

Evidence of the exact combination

No controlled clinical validation of this exact marketed combination was established in this review. Ingredient evidence is not combination evidence.

Component links are not combination evidence. A commercial name’s composition may vary.

Uncertainty and risks

Treating a vitamin deficiency does not establish weight loss or the safety of a multi-ingredient product.

Observed in supplier/community material; prevalence not quantified.

No dosing or mixing instructions are provided.

Source issues and references

References include queries and bibliographic handbook attributions; not all are clinical studies. Human review remains pending.

1. ODS-B12

   NIH ODS: Vitamin B12

   October 16, 2026

2. ODS-CHOLINE

   NIH ODS: Choline

   October 16, 2026

3. PC-CHOLINE

   PubChem choline (CID 305)

   October 16, 2026

4. PC-INOSITOL

   PubChem myo-inositol (CID 892)

   October 16, 2026

5. PC-METHIONINE

   PubChem L-methionine (CID 6137)

   October 16, 2026

6. PMID40920401

   Myo-inositol Supplementation to Prevent Pregnancy Complications in Polycystic Ovary Syndrome: A Randomized Clinical Trial.

   van der Wel AWT, Frank CMC, Bout-Rebel R, Duijnhoven RG, van Bree BE, Valkenburg O, Al-Nasiry S, van Oppenraaij RHF, Vogelvang TE, Westerhuis MEMH, van de Nieuwenhof HP, Gielen SCJP, Bandell ML, Bekker MN, Wouters MGAJ, Mijatovic V, Franx A, Lambalk CB, Broekmans FJM, de Weerd S, Gerards JMH, Baalman JH, van Disseldorp J, Langenveld J, Gunning MN, Frederix GWJ, Painter RC, Fauser BCJM, Laven JSE, van Rijn BB.

   DOI: 10.1001/jama.2025.13668PMID: 40920401

   October 16, 2026

7. SEARCH-PUBMED-b12

   PubMed/MED targeted search: TITLE:"vitamin B12" AND TITLE:randomised

   October 16, 2026

8. SEARCH-PUBMED-choline

   PubMed/MED targeted search: TITLE_ABS:choline AND TITLE_ABS:deficiency AND TITLE_ABS:human

   October 16, 2026

9. SEARCH-PUBMED-inositol

   PubMed/MED targeted search: TITLE_ABS:inositol AND TITLE_ABS:"polycystic ovary" AND TITLE_ABS:randomized

   October 16, 2026

10. SEARCH-PUBMED-methionine

    PubMed/MED targeted search: TITLE_ABS:methionine AND TITLE_ABS:homocysteine AND TITLE_ABS:human

    October 16, 2026

11. pdf01

    PEPNEXA 2.pdf

    October 16, 2026

12. pdf05

    PEPNEXA.pdf

    October 16, 2026

13. pdf07

    US Peptide MangerCorp(1).pdf

    October 16, 2026

14. pdf09

    PeptideFactory.pdf

    October 16, 2026