Metabolism and weight management
Conceptual educational illustration of Dulaglutide in a glass vial, labelled MOLECULE PROFILE.

View full illustrationSave Dulaglutide

MOLECULE PROFILE

Dulaglutide

Protein or biologic

GLP-1 receptor agonist fused to an Fc component; biologic distinct from semaglutide.

Sources checked · October 16, 2026

Published for review · Scientific, medical, translation and citation review pending. Reported uses are not authorized indications. Frequency reflects mentions in supplied sources, not sales or global clinical prevalence.

Identity and synonyms

Catalog label is recorded; analytical identity and equivalence are not established.

Protein or biologic · Fusion protein

Detailed molecular class: Protein/biologic; confirm exact product

Supplied sequence or chemical reference

Mechanism

GLP-1 receptor agonist fused to an Fc component; biologic distinct from semaglutide.

Evidence and critical reading

Reported scientific and empirical uses

Reported glycemic control · Cardiovascular and vascular function

Authorized type 2 diabetes treatment and reduction of certain cardiovascular events per Trulicity labeling; do not substitute other agonists’ obesity research.

Human evidence

REWIND studied cardiovascular outcomes in type 2 diabetes. An authorized product’s indications do not authenticate catalog dulaglutide.

Preclinical evidence

Do not equate mechanism, cell culture or animal work with a clinical outcome. The specific level is detailed in the evidence assessment.

Critical reading and limitations

REWIND studied cardiovascular outcomes in type 2 diabetes. An authorized product’s indications do not authenticate catalog dulaglutide.

REWIND studied cardiovascular outcomes in type 2 diabetes. An authorized product’s indications do not authenticate catalog dulaglutide.

Source-specific regimens

Descriptive source observations, not individual recommendations.

Regulatory product labeling

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Human-study exposure

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Empirical handbook

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Regulation and safety

Jurisdiction-specific regulatory context

EU: Trulicity is authorized for insufficiently controlled type 2 diabetes in patients ≥10 years with diet/exercise and label conditions. Commercial material does not inherit authorization.

Adverse effects and unknowns

Gastrointestinal, pancreatic/biliary risks and hypoglycemia with insulin/secretagogues. US MTC/MEN2 contraindication; verify jurisdictional labeling.

Contraindications

A complete list must match the exact authorized product. For experimental materials without verified human labeling, a complete contraindication set is not established here. No list does not mean safety.

Interactions

Separate documented interaction, pharmacologic plausibility and unknown interaction. Absence of a blend trial does not establish compatibility.

Studies and trials

Selected studies

No selected studies are attributed in this record.

Trials attributed in the package

No trials are attributed in this record.

Trial registration does not establish efficacy or validate commercial material.

Query candidates; attribution pending

Dulaglutide · 142 unfiltered query results, not authenticated trials

Query verification: October 16, 2026

Exact phrase intervention query; first three most recently updated records, not exhaustive. Aliases may be missed and heterogeneous products may appear. The total is the unfiltered registry query count, not authenticated trials. Source-integrity holds are excluded from ordinary listings.

View trial registry query

NCT05478707 · Therapeutic Strategies for Microvascular Dysfunction in Type 1 DiabetesRegistry status: RecruitingLast update posted: October 15, 2026Query verification: October 16, 2026

NCT07668336 · A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 DiabetesRegistry status: Not yet recruitingLast update posted: September 25, 2026Query verification: October 16, 2026

NCT07834398 · Weekly GLP-1 Receptor Agonists in Obese Individuals Without DiabetesRegistry status: CompletedLast update posted: September 22, 2026Query verification: October 16, 2026

Source issues and references

References include queries and bibliographic handbook attributions; not all are clinical studies. Human review remains pending.

  1. EMA-TRU

    Trulicity EMA EPAR

    October 16, 2026

  2. PMID31189511

    Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial.

    Gerstein HC, Colhoun HM, Dagenais GR, Diaz R, Lakshmanan M, Pais P, Probstfield J, Riesmeyer JS, Riddle MC, Rydén L, Xavier D, Atisso CM, Dyal L, Hall S, Rao-Melacini P, Wong G, Avezum A, Basile J, Chung N, Conget I, Cushman WC, Franek E, Hancu N, Hanefeld M, Holt S, Jansky P, Keltai M, Lanas F, Leiter LA, Lopez-Jaramillo P, Cardona Munoz EG, Pirags V, Pogosova N, Raubenheimer PJ, Shaw JE, Sheu WH, Temelkova-Kurktschiev T, REWIND Investigators.

    October 16, 2026

  3. SEARCH-PUBMED-dulaglutide

    PubMed/MED targeted search: TITLE:dulaglutide AND TITLE:REWIND

    October 16, 2026

  4. pdf07

    US Peptide MangerCorp(1).pdf

    October 16, 2026

  5. pdf09

    PeptideFactory.pdf

    October 16, 2026

A community-based bilingual scientific education initiative for healthcare professionals and the general public across the Americas.Currently self-funded; no current sponsors. Formal governance and legal documentation pending.info@peptideamericas.org · Planned contact address — not active yet; please do not send messages.