Nutrients and cofactors
Conceptual educational illustration of Folic acid in a glass specimen jar, labelled MOLECULE PROFILE.

View full illustrationSave Folic acid

AGENT PROFILE

Folic acid

Nonpeptide agent

Synthetic folate form, a one-carbon-metabolism/nucleotide-synthesis nutrient.

Sources checked · October 16, 2026

Published for review · Scientific, medical, translation and citation review pending. Reported uses are not authorized indications. Frequency reflects mentions in supplied sources, not sales or global clinical prevalence.

Identity and synonyms

Catalog label is recorded; analytical identity and equivalence are not established.

Nonpeptide agent · Vitamin or precursor

Detailed molecular class: Nonpeptide agent; see mechanism for subtype

Supplied sequence or chemical reference

PubChem CID: 135398658

Molecular formula: C19H19N7O6

IUPAC: (2S)-2-[[4-[(2-amino-4-oxo-3H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid

Source: PC-FOLIC-ACID

PubChem

Chemical structure reference

Database chemical reference; does not certify supplier vial, salt, isomer or formulation.

Mechanism

Synthetic folate form, a one-carbon-metabolism/nucleotide-synthesis nutrient.

Evidence and critical reading

Reported scientific and empirical uses

Hematologic context · Replacement and nutritional context

Neural-tube-defect prevention/deficiency correction in defined contexts; not equivalent to aesthetic blends.

Human evidence

Preventive evidence concerns periconceptional timing/specific exposure. It does not establish the same outcome for every multivitamin formulation.

Preclinical evidence

Do not equate mechanism, cell culture or animal work with a clinical outcome. The specific level is detailed in the evidence assessment.

Critical reading and limitations

Preventive evidence concerns periconceptional timing/specific exposure. It does not establish the same outcome for every multivitamin formulation.

Preventive evidence concerns periconceptional timing/specific exposure. It does not establish the same outcome for every multivitamin formulation.

Source-specific regimens

Descriptive source observations, not individual recommendations.

Regulatory product labeling

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Human-study exposure

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Empirical handbook

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Regulation and safety

Jurisdiction-specific regulatory context

This record does not verify FDA/EMA authorization of the commercial identity. Where a specific medicine/product exists, jurisdiction/indication are detailed in cited sources; they do not transfer to supplier material.

Adverse effects and unknowns

High amounts may correct anemia and mask B12 deficiency without resolving neurological damage. Antifolates/other medicines need contextual review.

Contraindications

A complete list must match the exact authorized product. For experimental materials without verified human labeling, a complete contraindication set is not established here. No list does not mean safety.

Interactions

Separate documented interaction, pharmacologic plausibility and unknown interaction. Absence of a blend trial does not establish compatibility.

Studies and trials

Selected studies

No selected studies are attributed in this record.

Trials attributed in the package

No trials are attributed in this record.

Trial registration does not establish efficacy or validate commercial material.

Query candidates; attribution pending

Folic acid · 2735 unfiltered query results, not authenticated trials

Query verification: October 16, 2026

Exact phrase intervention query; first three most recently updated records, not exhaustive. Aliases may be missed and heterogeneous products may appear. The total is the unfiltered registry query count, not authenticated trials. Source-integrity holds are excluded from ordinary listings.

View trial registry query

NCT07770711 · Inositol and Metformin Administration in Mediterranean Diet and Low-Carbohydrate Diets in Women With PCOSRegistry status: RecruitingLast update posted: October 16, 2026Query verification: October 16, 2026

NCT07554521 · A Study to Evaluate Efficacy and Safety of Tislelizumab Plus Chemotherapy for Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Adenocarcinoma and Esophageal Squamous Cell Carcinoma in Racial and Ethnic Minority Patients in the United StatesRegistry status: RecruitingLast update posted: October 16, 2026Query verification: October 16, 2026

NCT07431281 · Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2Registry status: RecruitingLast update posted: October 16, 2026Query verification: October 16, 2026

Source issues and references

References include queries and bibliographic handbook attributions; not all are clinical studies. Human review remains pending.

  1. ODS-FOLATE

    NIH ODS: Folate

    October 16, 2026

  2. PC-FOLIC-ACID

    PubChem folic acid (CID 135398658)

    October 16, 2026

  3. SEARCH-PUBMED-folic-acid

    PubMed/MED targeted search: TITLE_ABS:"folic acid" AND TITLE_ABS:"neural tube" AND TITLE_ABS:randomised

    October 16, 2026

A community-based bilingual scientific education initiative for healthcare professionals and the general public across the Americas.Currently self-funded; no current sponsors. Formal governance and legal documentation pending.info@peptideamericas.org · Planned contact address — not active yet; please do not send messages.