GH/IGF axis
Conceptual educational illustration of Hexarelin in a glass vial, labelled MOLECULE PROFILE.

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MOLECULE PROFILE

Hexarelin

Peptide or peptide-related

Peptide GH secretagogue; acute endocrine response is not demonstrated muscle growth.

Sources checked · October 16, 2026

Published for review · Scientific, medical, translation and citation review pending. Reported uses are not authorized indications. Frequency reflects mentions in supplied sources, not sales or global clinical prevalence.

Identity and synonyms

Catalog label is recorded; analytical identity and equivalence are not established.

Peptide or peptide-related · Peptide or peptide derivative

Detailed molecular class: Peptide or peptide-derivative label; see identity

Supplied sequence or chemical reference

Mechanism

Peptide GH secretagogue; acute endocrine response is not demonstrated muscle growth.

Evidence and critical reading

Reported scientific and empirical uses

GH/IGF hormonal axis

Mentioned for GH, recovery and body composition; distinguish these uses from brief physiology experiments.

Human evidence

A study in six normal young men examined subcutaneous administrations over 24 hours: GH secretion increased without an IGF-1 change. It did not measure chronic functional benefit.

Preclinical evidence

Do not equate mechanism, cell culture or animal work with a clinical outcome. The specific level is detailed in the evidence assessment.

Critical reading and limitations

A study in six normal young men examined subcutaneous administrations over 24 hours: GH secretion increased without an IGF-1 change. It did not measure chronic functional benefit.

A study in six normal young men examined subcutaneous administrations over 24 hours: GH secretion increased without an IGF-1 change. It did not measure chronic functional benefit.

Source-specific regimens

Descriptive source observations, not individual recommendations.

Regulatory product labeling

Listed regimens preserve source/context. An empty layer means no regimen attributable to this identity was verified in this review; it does not prove universal absence of data.

Human-study exposure

NOT A RECOMMENDATION.Each amount is attributed to the source identified for that entry: regulatory product labeling, human research, or community and practice sources. These source categories have different evidentiary roles. They are not medical advice, not a protocol, not a recommended or safe dose, and not evidence that it works. Do not use them to start, change or stop any treatment. Talk to a qualified healthcare professional.

Reported by Impact of two or three daily subcutaneous injections of hexarelin, a synthetic growth hormone (GH) secretagogue, on 24-h GH, prolactin, adrenocorticotropin and cortisol secretion in humans.

1.5 mcg/kg · Amount per administration

Frequency
Two or three administrations over 24 hours
Duration
24 hours
Route
Subcutaneous
Context
Six normal men; GH physiology, not chronic anabolic efficacy.
Presentation
A dosage-form presentation is not specified in the reviewed record.
Interpretation
Research exposure: not a prescription or starting regimen. It does not reconstruct protocol titration, exclusions or monitoring.

PMID11888836 · October 16, 2026

NOT A RECOMMENDATION.Each amount is attributed to the source identified for that entry: regulatory product labeling, human research, or community and practice sources. These source categories have different evidentiary roles. They are not medical advice, not a protocol, not a recommended or safe dose, and not evidence that it works. Do not use them to start, change or stop any treatment. Talk to a qualified healthcare professional.

Empirical handbook

Listed regimens preserve source/context. An empty layer means no regimen attributable to this identity was verified in this review; it does not prove universal absence of data.

Regulation and safety

Jurisdiction-specific regulatory context

This record does not verify FDA/EMA authorization of the commercial identity. Where a specific medicine/product exists, jurisdiction/indication are detailed in cited sources; they do not transfer to supplier material.

Adverse effects and unknowns

A sample of six cannot delimit uncommon effects or long-term GH-axis safety; a one-day experiment does not establish metabolic neutrality.

Contraindications

A complete list must match the exact authorized product. For experimental materials without verified human labeling, a complete contraindication set is not established here. No list does not mean safety.

Interactions

Separate documented interaction, pharmacologic plausibility and unknown interaction. Absence of a blend trial does not establish compatibility.

Studies and trials

Selected studies

PMID11888836 · Physiology experiment

Normal young men.

SC, 24 hours.

Increased GH secretion without an IGF-1 change.

Trial product/population; does not authenticate supplier material or permit simple indirect comparisons.

n = 6

Trials attributed in the package

No trials are attributed in this record.

Trial registration does not establish efficacy or validate commercial material.

Query candidates; attribution pending

Hexarelin · 0 unfiltered query results, not authenticated trials

Query verification: October 16, 2026

Exact phrase intervention query; first three most recently updated records, not exhaustive. Aliases may be missed and heterogeneous products may appear. The total is the unfiltered registry query count, not authenticated trials. Source-integrity holds are excluded from ordinary listings.

View trial registry query

Source issues and references

References include queries and bibliographic handbook attributions; not all are clinical studies. Human review remains pending.

  1. PMID11888836

    Impact of two or three daily subcutaneous injections of hexarelin, a synthetic growth hormone (GH) secretagogue, on 24-h GH, prolactin, adrenocorticotropin and cortisol secretion in humans.

    Maccario M, Veldhuis JD, Broglio F, Vito LD, Arvat E, Deghenghi R, Ghigo E.

    October 16, 2026

  2. SEARCH-PUBMED-hexarelin

    PubMed/MED targeted search: TITLE_ABS:hexarelin AND TITLE_ABS:healthy AND TITLE_ABS:men

    October 16, 2026

  3. pdf01

    PEPNEXA 2.pdf

    October 16, 2026

  4. pdf02

    ELLA PEPTIDES.pdf

    October 16, 2026

  5. pdf03

    zlz list 26.8.5.pdf

    October 16, 2026

  6. pdf05

    PEPNEXA.pdf

    October 16, 2026

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