Metabolism and weight management
Conceptual educational illustration of Pancragen in a glass vial, labelled MOLECULE PROFILE.

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MOLECULE PROFILE

Pancragen

Peptide or peptide-related

Tetrapeptide bioregulator studied in pancreatic function; the name does not identify an authorized antidiabetic therapy.

Sources checked · October 16, 2026

Published for review · Scientific, medical, translation and citation review pending. Reported uses are not authorized indications. Frequency reflects mentions in supplied sources, not sales or global clinical prevalence.

Identity and synonyms

Catalog label is recorded; analytical identity and equivalence are not established.

Peptide or peptide-related · Peptide or peptide derivative

Detailed molecular class: Peptide or peptide-derivative label; see identity

Supplied sequence or chemical reference

Mechanism

Tetrapeptide bioregulator studied in pancreatic function; the name does not identify an authorized antidiabetic therapy.

Evidence and critical reading

Reported scientific and empirical uses

Reported glycemic control

Promoted for glucose/pancreatic aging; distinguish primate studies from human trials.

Human evidence

The 2017 study included nine old female rhesus monkeys: five received Pancragen/four glimepiride. Animal metabolic changes establish neither human efficacy nor a human dose.

Preclinical evidence

Do not equate mechanism, cell culture or animal work with a clinical outcome. The specific level is detailed in the evidence assessment.

Critical reading and limitations

The 2017 study included nine old female rhesus monkeys: five received Pancragen/four glimepiride. Animal metabolic changes establish neither human efficacy nor a human dose.

The 2017 study included nine old female rhesus monkeys: five received Pancragen/four glimepiride. Animal metabolic changes establish neither human efficacy nor a human dose.

Source-specific regimens

Descriptive source observations, not individual recommendations.

Regulatory product labeling

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Human-study exposure

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Empirical handbook

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Regulation and safety

Jurisdiction-specific regulatory context

This record does not verify FDA/EMA authorization of the commercial identity. Where a specific medicine/product exists, jurisdiction/indication are detailed in cited sources; they do not transfer to supplier material.

Adverse effects and unknowns

Do not infer clinical safety from nutrients or an animal antidiabetic comparison. Combination with glucose-lowering medicines remains uncharacterized.

Contraindications

A complete list must match the exact authorized product. For experimental materials without verified human labeling, a complete contraindication set is not established here. No list does not mean safety.

Interactions

Separate documented interaction, pharmacologic plausibility and unknown interaction. Absence of a blend trial does not establish compatibility.

Studies and trials

Selected studies

PMID28509500 · Animal experiment

Old female rhesus monkeys: 5 Pancragen, 4 glimepiride.

Animal experiment.

Glucose-tolerance/hormone changes.

Nonhuman primate; no human regimen/established antidiabetic efficacy.

n = 9

Trials attributed in the package

No trials are attributed in this record.

Trial registration does not establish efficacy or validate commercial material.

Query candidates; attribution pending

Pancragen · 0 unfiltered query results, not authenticated trials

Query verification: October 16, 2026

Exact phrase intervention query; first three most recently updated records, not exhaustive. Aliases may be missed and heterogeneous products may appear. The total is the unfiltered registry query count, not authenticated trials. Source-integrity holds are excluded from ordinary listings.

View trial registry query

Source issues and references

References include queries and bibliographic handbook attributions; not all are clinical studies. Human review remains pending.

  1. PMID25946840

    [Impact of tetrapeptide pancragen on endocrine function of the pancreas in old monkeys].

    Goncharova ND, Ivanova LG, Oganian TÉ, Vengerin AA, Khavinson VKh.

    October 16, 2026

  2. PMID28509500

    [Correction of impaired glucose tolerance using tetrapeptide (Pancragen) in old female rhesus monkeys].

    Goncharova ND, Ivanova LG, Oganyan TE, Vengerin AA, Khavinson VK.

    October 16, 2026

  3. SEARCH-PUBMED-pancragen

    PubMed/MED targeted search: TITLE_ABS:pancragen

    October 16, 2026

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