Metabolism and weight management
Conceptual educational illustration of 5-amino-1MQ in a glass specimen jar, labelled MOLECULE PROFILE.

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AGENT PROFILE

5-amino-1MQ

Nonpeptide agent

NNMT inhibition; NNMT methylates nicotinamide, not NAD directly.

Sources checked · October 16, 2026

Published for review · Scientific, medical, translation and citation review pending. Reported uses are not authorized indications. Frequency reflects mentions in supplied sources, not sales or global clinical prevalence.

Identity and synonyms

Identity follows the supplied name and synonyms; no additional identity description is supplied.

Synonyms: 5-amino-1-methylquinolinium · 5-amino-1mg (source spelling; identity to confirm)

Nonpeptide agent · Nonpeptide small molecule

Detailed molecular class: Non-peptide small molecule

Supplied sequence or chemical reference

PubChem CID: 950107

Molecular formula: C10H11N2+

IUPAC: 1-methylquinolin-1-ium-5-amine

Source: PC-5-AMINO-1MQ

PubChem

Chemical structure reference

Database chemical reference; does not certify supplier vial, salt, isomer or formulation.

Mechanism

NNMT inhibition; NNMT methylates nicotinamide, not NAD directly.

Evidence and critical reading

Reported scientific and empirical uses

Reported weight management

Small-molecule NNMT inhibitor sold alongside peptides; not a peptide.

Human evidence

No clinical obesity or longevity efficacy established by the cited mouse study.

Preclinical evidence

Diet-induced obesity experiments in mice.

Critical reading and limitations

The selected obese-mouse study establishes neither human efficacy nor equivalence of commercial salts.

Evidence applies to the exact molecule, formulation, route, population and endpoint studied. Supplier identity, purity and clinical equivalence are unverified.

Source-specific regimens

Descriptive source observations, not individual recommendations.

Regulatory product labeling

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Human-study exposure

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Empirical handbook

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Regulation and safety

Jurisdiction-specific regulatory context

Jurisdiction-specific approval not verified in this card; do not infer global nonapproval.

Adverse effects and unknowns

Human toxicity, interactions and therapeutic window unresolved.

No validated human regimen; systemic enzyme inhibition/interactions cannot be declared harmless.

Contraindications

See supported safety statements and exact product label; a complete contraindication set has not been established for this catalog material.

A complete list must match the exact authorized product. For experimental materials without verified human labeling, a complete contraindication set is not established here. No list does not mean safety.

Interactions

Only explicitly cited interactions may be asserted; unstudied combinations remain unknown, not interaction-free.

Separate documented interaction, pharmacologic plausibility and unknown interaction. Absence of a blend trial does not establish compatibility.

Studies and trials

Selected studies

No selected studies are attributed in this record.

Trials attributed in the package

No trials are attributed in this record.

Trial registration does not establish efficacy or validate commercial material.

Query candidates; attribution pending

5-amino-1MQ · 0 unfiltered query results, not authenticated trials

Query verification: October 16, 2026

Exact phrase intervention query; first three most recently updated records, not exhaustive. Aliases may be missed and heterogeneous products may appear. The total is the unfiltered registry query count, not authenticated trials. Source-integrity holds are excluded from ordinary listings.

View trial registry query

Source issues and references

References include queries and bibliographic handbook attributions; not all are clinical studies. Human review remains pending.

  1. PC-5-AMINO-1MQ

    PubChem 5-amino-1-methylquinolinium (CID 950107)

    October 16, 2026

  2. PMID29155147

    Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice.

    Neelakantan H, Vance V, Wetzel MD, Wang HL, McHardy SF, Finnerty CC, Hommel JD, Watowich SJ.

    October 16, 2026

  3. R26

    Neelakantan et al.: NNMT inhibitors in obese mice, 2018

  4. pdf01

    PEPNEXA 2.pdf

    October 16, 2026

  5. pdf02

    ELLA PEPTIDES.pdf

    October 16, 2026

  6. pdf03

    zlz list 26.8.5.pdf

    October 16, 2026

  7. pdf05

    PEPNEXA.pdf

    October 16, 2026

  8. pdf07

    US Peptide MangerCorp(1).pdf

    October 16, 2026

  9. pdf09

    PeptideFactory.pdf

    October 16, 2026

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