Identity and synonyms
Catalog label is recorded; analytical identity and equivalence are not established.
Peptide or peptide-related · Peptide or peptide derivative
Detailed molecular class: Peptide or peptide-derivative label; see identity
Supplied sequence or chemical reference
Mechanism
ACTH stimulates adrenal corticosteroid production through melanocortin receptors; not equivalent to every corticotropin preparation.
Evidence and critical reading
Reported scientific and empirical uses
Immune modulation and inflammation
Endocrine/immunologic contexts in authorized products; the catalog specifies a peptide length requiring confirmation.
Human evidence
Acthar Gel is repository corticotropin with its own product composition. Its label does not prove commercial synthetic ACTH 1–39 identity, units or regimen.
Preclinical evidence
Do not equate mechanism, cell culture or animal work with a clinical outcome. The specific level is detailed in the evidence assessment.
Critical reading and limitations
Acthar Gel is repository corticotropin with its own product composition. Its label does not prove commercial synthetic ACTH 1–39 identity, units or regimen.
Acthar Gel is repository corticotropin with its own product composition. Its label does not prove commercial synthetic ACTH 1–39 identity, units or regimen.
Source-specific regimens
Descriptive source observations, not individual recommendations.
Regulatory product labeling
No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.
Human-study exposure
No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.
Empirical handbook
No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.
Regulation and safety
Jurisdiction-specific regulatory context
US: Acthar Gel has indications for a repository corticotropin preparation. It does not verify authorization/equivalence of a synthetic product called ACTH 1–39.
Adverse effects and unknowns
Glucocorticoid exposure can involve infection, hyperglycemia, hypertension and axis suppression; assess exact labeling/concomitant therapies.
Contraindications
A complete list must match the exact authorized product. For experimental materials without verified human labeling, a complete contraindication set is not established here. No list does not mean safety.
Interactions
Separate documented interaction, pharmacologic plausibility and unknown interaction. Absence of a blend trial does not establish compatibility.
Studies and trials
Selected studies
No selected studies are attributed in this record.
Trials attributed in the package
No trials are attributed in this record.
Trial registration does not establish efficacy or validate commercial material.
Query candidates; attribution pending
ACTH 1–39 · 223 unfiltered query results, not authenticated trials
Query verification: October 16, 2026
Exact phrase intervention query; first three most recently updated records, not exhaustive. Aliases may be missed and heterogeneous products may appear. The total is the unfiltered registry query count, not authenticated trials. Source-integrity holds are excluded from ordinary listings.
View trial registry queryNCT01960530 · An Investigational Study of HydrocortisoneRegistry status: CompletedLast update posted: October 2, 2026Query verification: October 16, 2026
NCT07833163 · Corticotropin for Behçet's Disease: A Multicenter Randomized Controlled TrialAcronym.Registry status: Not yet recruitingLast update posted: September 22, 2026Query verification: October 16, 2026
NCT05907291 · Evaluate the Safety, Efficacy, and Pharmacokinetics of CRN04894 in Participants With Congenital Adrenal Hyperplasia (TouCAHn)Registry status: CompletedLast update posted: September 10, 2026Query verification: October 16, 2026
Source issues and references
References include queries and bibliographic handbook attributions; not all are clinical studies. Human review remains pending.
- REG-ACTHAR
DailyMed: Acthar Gel repository corticotropin
October 16, 2026
- SEARCH-PUBMED-acth-1-39
October 16, 2026
- pdf07
US Peptide MangerCorp(1).pdf
October 16, 2026