Vascular signaling
Conceptual educational illustration of B7-33 in a glass vial, labelled MOLECULE PROFILE.

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MOLECULE PROFILE

B7-33

Peptide or peptide-related

Functionally selective RXFP1 agonist derived from relaxin research.

Sources checked · October 16, 2026

Published for review · Scientific, medical, translation and citation review pending. Reported uses are not authorized indications. Frequency reflects mentions in supplied sources, not sales or global clinical prevalence.

Identity and synonyms

Identity follows the supplied name and synonyms; no additional identity description is supplied.

Peptide or peptide-related · Peptide or peptide derivative

Detailed molecular class: Peptide

Supplied sequence or chemical reference

See identity note; no supplier sequence accepted as verification.

Mechanism

Functionally selective RXFP1 agonist derived from relaxin research.

Evidence and critical reading

Reported scientific and empirical uses

Recovery and connective tissue · Cardiovascular and vascular function

Relaxin derivative investigated for fibrosis/remodeling; not the complete hormone.

Human evidence

No controlled human efficacy finding was verified for the exact catalog identity in this screen.

Preclinical evidence

Attenuated adverse cardiac remodeling after myocardial infarction in mice.

Critical reading and limitations

A mouse infarction model supports a hypothesis, not human fibrosis/heart-failure treatment.

Evidence applies to the exact molecule, formulation, route, population and endpoint studied. Supplier identity, purity and clinical equivalence are unverified.

Source-specific regimens

Descriptive source observations, not individual recommendations.

Regulatory product labeling

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Human-study exposure

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Empirical handbook

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Regulation and safety

Jurisdiction-specific regulatory context

Jurisdiction-specific approval not verified in this card; do not infer global nonapproval.

Adverse effects and unknowns

Human safety, contraindications and interactions are not adequately established for the catalog product. Missing reports are not evidence of safety.

Human dosing, interactions and commercial-vial clinical safety are not established.

Contraindications

See supported safety statements and exact product label; a complete contraindication set has not been established for this catalog material.

A complete list must match the exact authorized product. For experimental materials without verified human labeling, a complete contraindication set is not established here. No list does not mean safety.

Interactions

Only explicitly cited interactions may be asserted; unstudied combinations remain unknown, not interaction-free.

Separate documented interaction, pharmacologic plausibility and unknown interaction. Absence of a blend trial does not establish compatibility.

Studies and trials

Selected studies

No selected studies are attributed in this record.

Trials attributed in the package

No trials are attributed in this record.

Trial registration does not establish efficacy or validate commercial material.

Query candidates; attribution pending

B7-33 · 0 unfiltered query results, not authenticated trials

Query verification: October 16, 2026

Exact phrase intervention query; first three most recently updated records, not exhaustive. Aliases may be missed and heterogeneous products may appear. The total is the unfiltered registry query count, not authenticated trials. Source-integrity holds are excluded from ordinary listings.

View trial registry query

Source issues and references

References include queries and bibliographic handbook attributions; not all are clinical studies. Human review remains pending.

  1. PMID32295457

    B7-33, a Functionally Selective Relaxin Receptor 1 Agonist, Attenuates Myocardial Infarction-Related Adverse Cardiac Remodeling in Mice.

    Devarakonda T, Mauro AG, Guzman G, Hovsepian S, Cain C, Das A, Praveen P, Hossain MA, Salloum FN.

    October 16, 2026

  2. pdf01

    PEPNEXA 2.pdf

    October 16, 2026

  3. pdf05

    PEPNEXA.pdf

    October 16, 2026

  4. pdf07

    US Peptide MangerCorp(1).pdf

    October 16, 2026

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