Nutrients and cofactors
Conceptual educational illustration of Choline in a glass specimen jar, labelled MOLECULE PROFILE.

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AGENT PROFILE

Choline

Nonpeptide agent

Nutrient precursor of phospholipids/acetylcholine; not a peptide or inherently a lipolytic drug.

Sources checked · October 16, 2026

Published for review · Scientific, medical, translation and citation review pending. Reported uses are not authorized indications. Frequency reflects mentions in supplied sources, not sales or global clinical prevalence.

Identity and synonyms

Catalog label is recorded; analytical identity and equivalence are not established.

Nonpeptide agent · Nonpeptide small molecule

Detailed molecular class: Nonpeptide agent; see mechanism for subtype

Supplied sequence or chemical reference

PubChem CID: 305

Molecular formula: C5H14NO+

IUPAC: 2-hydroxyethyl(trimethyl)azanium

Source: PC-CHOLINE

PubChem

Chemical structure reference

Database chemical reference; does not certify supplier vial, salt, isomer or formulation.

Mechanism

Nutrient precursor of phospholipids/acetylcholine; not a peptide or inherently a lipolytic drug.

Evidence and critical reading

Reported scientific and empirical uses

Replacement and nutritional context

Nutrition/deficiency prevention; MIC’s attributed hepatic/lipotropic effects require formulation-specific clinical proof.

Human evidence

Deficiency can affect liver/muscle. That physiological need does not establish injectable-blend slimming or cognition benefits in replete people.

Preclinical evidence

Do not equate mechanism, cell culture or animal work with a clinical outcome. The specific level is detailed in the evidence assessment.

Critical reading and limitations

Deficiency can affect liver/muscle. That physiological need does not establish injectable-blend slimming or cognition benefits in replete people.

Deficiency can affect liver/muscle. That physiological need does not establish injectable-blend slimming or cognition benefits in replete people.

Source-specific regimens

Descriptive source observations, not individual recommendations.

Regulatory product labeling

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Human-study exposure

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Empirical handbook

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Regulation and safety

Jurisdiction-specific regulatory context

This record does not verify FDA/EMA authorization of the commercial identity. Where a specific medicine/product exists, jurisdiction/indication are detailed in cited sources; they do not transfer to supplier material.

Adverse effects and unknowns

Excess intake can cause body odor, vomiting and hypotension per institutional review; dietary limits cannot be extrapolated to injection.

Contraindications

A complete list must match the exact authorized product. For experimental materials without verified human labeling, a complete contraindication set is not established here. No list does not mean safety.

Interactions

Separate documented interaction, pharmacologic plausibility and unknown interaction. Absence of a blend trial does not establish compatibility.

Studies and trials

Selected studies

No selected studies are attributed in this record.

Trials attributed in the package

No trials are attributed in this record.

Trial registration does not establish efficacy or validate commercial material.

Query candidates; attribution pending

Choline · 381 unfiltered query results, not authenticated trials

Query verification: October 16, 2026

Exact phrase intervention query; first three most recently updated records, not exhaustive. Aliases may be missed and heterogeneous products may appear. The total is the unfiltered registry query count, not authenticated trials. Source-integrity holds are excluded from ordinary listings.

View trial registry query

NCT07450664 · Observational Study of VYKAT™ XR in Patients With Prader-Willi SyndromeRegistry status: Enrolling by invitationLast update posted: October 14, 2026Query verification: October 16, 2026

NCT05532020 · An Open-Label Study of Diazoxide Choline in Patients With Genetic ObesitiesRegistry status: WithdrawnLast update posted: October 13, 2026Query verification: October 16, 2026

NCT05701774 · Open-Label Extension Study of DCCR in Patients With Prader-Willi SyndromeRegistry status: CompletedLast update posted: October 13, 2026Query verification: October 16, 2026

Source issues and references

References include queries and bibliographic handbook attributions; not all are clinical studies. Human review remains pending.

  1. ODS-CHOLINE

    NIH ODS: Choline

    October 16, 2026

  2. PC-CHOLINE

    PubChem choline (CID 305)

    October 16, 2026

  3. SEARCH-PUBMED-choline

    PubMed/MED targeted search: TITLE_ABS:choline AND TITLE_ABS:deficiency AND TITLE_ABS:human

    October 16, 2026

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