Nutrients and cofactors
Conceptual educational illustration of Methionine in a glass specimen jar, labelled MOLECULE PROFILE.

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AGENT PROFILE

Methionine

Nonpeptide agent

Essential amino acid, S-adenosylmethionine precursor and participant in one-carbon metabolism.

Sources checked · October 16, 2026

Published for review · Scientific, medical, translation and citation review pending. Reported uses are not authorized indications. Frequency reflects mentions in supplied sources, not sales or global clinical prevalence.

Identity and synonyms

Catalog label is recorded; analytical identity and equivalence are not established.

Nonpeptide agent · Amino acid or derivative

Detailed molecular class: Nonpeptide agent; see mechanism for subtype

Supplied sequence or chemical reference

PubChem CID: 6137

Molecular formula: C5H11NO2S

IUPAC: (2S)-2-amino-4-methylsulfanylbutanoic acid

Source: PC-METHIONINE

PubChem

Chemical structure reference

Database chemical reference; does not certify supplier vial, salt, isomer or formulation.

Mechanism

Essential amino acid, S-adenosylmethionine precursor and participant in one-carbon metabolism.

Evidence and critical reading

Reported scientific and empirical uses

Replacement and nutritional context

MIC/Lipo-C ingredient under a “lipotropic” narrative; methionine is neither SAMe nor a standardized MIC blend.

Human evidence

Nutritional function does not establish fat loss from parenteral methionine or blend synergy. No human regimen was assigned for that aim.

Preclinical evidence

Do not equate mechanism, cell culture or animal work with a clinical outcome. The specific level is detailed in the evidence assessment.

Critical reading and limitations

Nutritional function does not establish fat loss from parenteral methionine or blend synergy. No human regimen was assigned for that aim.

Nutritional function does not establish fat loss from parenteral methionine or blend synergy. No human regimen was assigned for that aim.

Source-specific regimens

Descriptive source observations, not individual recommendations.

Regulatory product labeling

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Human-study exposure

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Empirical handbook

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Regulation and safety

Jurisdiction-specific regulatory context

This record does not verify FDA/EMA authorization of the commercial identity. Where a specific medicine/product exists, jurisdiction/indication are detailed in cited sources; they do not transfer to supplier material.

Adverse effects and unknowns

Homocysteine metabolism and folate/B12 status matter. An essential nutrient is not harmless at every dose/route.

Contraindications

A complete list must match the exact authorized product. For experimental materials without verified human labeling, a complete contraindication set is not established here. No list does not mean safety.

Interactions

Separate documented interaction, pharmacologic plausibility and unknown interaction. Absence of a blend trial does not establish compatibility.

Studies and trials

Selected studies

No selected studies are attributed in this record.

Trials attributed in the package

No trials are attributed in this record.

Trial registration does not establish efficacy or validate commercial material.

Query candidates; attribution pending

Methionine · 212 unfiltered query results, not authenticated trials

Query verification: October 16, 2026

Exact phrase intervention query; first three most recently updated records, not exhaustive. Aliases may be missed and heterogeneous products may appear. The total is the unfiltered registry query count, not authenticated trials. Source-integrity holds are excluded from ordinary listings.

View trial registry query

NCT07557615 · hCG Treatment for Rehabilitation From a TBIRegistry status: Not yet recruitingLast update posted: October 13, 2026Query verification: October 16, 2026

NCT02824419 · Imaging of Active Granulomas With [18F]FDG and Selected Inflammatory PET Tracers in Pulmonary SarcoidosisRegistry status: TerminatedLast update posted: October 7, 2026Query verification: October 16, 2026

NCT05400733 · Prandial Metabolic Phenotype in AdultsRegistry status: Active, not recruitingLast update posted: October 5, 2026Query verification: October 16, 2026

Source issues and references

References include queries and bibliographic handbook attributions; not all are clinical studies. Human review remains pending.

  1. PC-METHIONINE

    PubChem L-methionine (CID 6137)

    October 16, 2026

  2. SEARCH-PUBMED-methionine

    PubMed/MED targeted search: TITLE_ABS:methionine AND TITLE_ABS:homocysteine AND TITLE_ABS:human

    October 16, 2026

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