Nutrients and cofactors
Conceptual educational illustration of Thiamine in a glass specimen jar, labelled MOLECULE PROFILE.

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AGENT PROFILE

Thiamine

Nonpeptide agent

Nonpeptide vitamin B1; diphosphate form is an energy-metabolism cofactor.

Sources checked · October 16, 2026

Published for review · Scientific, medical, translation and citation review pending. Reported uses are not authorized indications. Frequency reflects mentions in supplied sources, not sales or global clinical prevalence.

Identity and synonyms

Catalog label is recorded; analytical identity and equivalence are not established.

Nonpeptide agent · Vitamin or precursor

Detailed molecular class: Nonpeptide agent; see mechanism for subtype

Supplied sequence or chemical reference

PubChem CID: 1130

Molecular formula: C12H17N4OS+

IUPAC: 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol

Source: PC-THIAMINE

PubChem

Chemical structure reference

Database chemical reference; does not certify supplier vial, salt, isomer or formulation.

Mechanism

Nonpeptide vitamin B1; diphosphate form is an energy-metabolism cofactor.

Evidence and critical reading

Reported scientific and empirical uses

Replacement and nutritional context

Deficiency correction/contexts such as Wernicke encephalopathy require specific care. Ingredient in hair/skin/nail blends.

Human evidence

Replacement evidence does not demonstrate cosmetic/energy benefit in replete people or efficacy of the commercial whole.

Preclinical evidence

Do not equate mechanism, cell culture or animal work with a clinical outcome. The specific level is detailed in the evidence assessment.

Critical reading and limitations

Replacement evidence does not demonstrate cosmetic/energy benefit in replete people or efficacy of the commercial whole.

Replacement evidence does not demonstrate cosmetic/energy benefit in replete people or efficacy of the commercial whole.

Source-specific regimens

Descriptive source observations, not individual recommendations.

Regulatory product labeling

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Human-study exposure

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Empirical handbook

No numerical human dose is assigned: reviewed sources did not verify a regimen attributable to this material, route and indication. Other molecules’ doses, animal exposures, vial amounts and dietary requirements are not substituted.

Regulation and safety

Jurisdiction-specific regulatory context

This record does not verify FDA/EMA authorization of the commercial identity. Where a specific medicine/product exists, jurisdiction/indication are detailed in cited sources; they do not transfer to supplier material.

Adverse effects and unknowns

Route/clinical urgency change treatment; nutritional amounts must not be turned into a parenteral wellness protocol.

Contraindications

A complete list must match the exact authorized product. For experimental materials without verified human labeling, a complete contraindication set is not established here. No list does not mean safety.

Interactions

Separate documented interaction, pharmacologic plausibility and unknown interaction. Absence of a blend trial does not establish compatibility.

Studies and trials

Selected studies

No selected studies are attributed in this record.

Trials attributed in the package

No trials are attributed in this record.

Trial registration does not establish efficacy or validate commercial material.

Query candidates; attribution pending

Thiamine · 268 unfiltered query results, not authenticated trials

Query verification: October 16, 2026

Exact phrase intervention query; first three most recently updated records, not exhaustive. Aliases may be missed and heterogeneous products may appear. The total is the unfiltered registry query count, not authenticated trials. Source-integrity holds are excluded from ordinary listings.

View trial registry query

NCT07877948 · Comparative Study of Combination Treatment of Bionerv E+ Versus Vitamin B Complex in Treatment of Diabetic Polyneuropathy in Type 2 Diabetic Patients and Its Effect on Wound HealingRegistry status: RecruitingLast update posted: October 16, 2026Query verification: October 16, 2026

NCT07752342 · Exploring Wellbeing Outcomes in Adolescents Using Bifidobacterium Longum, 1714™Registry status: Not yet recruitingLast update posted: October 14, 2026Query verification: October 16, 2026

NCT03059940 · Smoking Cessation Intervention During Low Dose CT (LDCT) Screening for Lung CancerRegistry status: Active, not recruitingLast update posted: October 13, 2026Query verification: October 16, 2026

Source issues and references

References include queries and bibliographic handbook attributions; not all are clinical studies. Human review remains pending.

  1. ODS-THIAMIN

    NIH ODS: Thiamin

    October 16, 2026

  2. PC-THIAMINE

    PubChem thiamine (CID 1130)

    October 16, 2026

A community-based bilingual scientific education initiative for healthcare professionals and the general public across the Americas.Currently self-funded; no current sponsors. Formal governance and legal documentation pending.info@peptideamericas.org · Planned contact address — not active yet; please do not send messages.