What a penetration study actually measures
Where material is found belongs in the result.
A diffusion cell answers a particular question.
Where material is found belongs in the result.
Follow the material
OECD 428 describes a skin sample separating donor and receptor compartments. The substance is applied and its distribution and passage are analyzed over time. Skin source, formulation and assay conditions accompany interpretation. This is an absorption method, not a trial of wrinkle improvement or wound healing.
Connect without conflating
Try two sentences when reading: “it was detected at this location” and “this benefit was measured.” If only the first exists, leave the second open. Also ask whether the intact compound was identified or whether the signal could have another explanation. Record missing information as a limitation rather than inventing an answer.
Professional context / Contexto profesional
Review analytical recovery, stability and identity of the measured material in the full report.
Evidence / Evidencia
Experimental skin-absorption method.
Limitations / Limitaciones
The description does not validate a commercial formulation or establish clinical efficacy.