Proposed questionnaire preview

Editorial feedback (not health-related) · 3

Would help decide what to explain next. Kept separate from research consent and membership preferences.

1. Q01Several choices

   Which topics should we explain next?

   • Recovery
   • Metabolic
   • Skin
   • Gut and immune
   • Brain and sleep
   • Mitochondria
   • Product quality
   • Evidence methods
2. Q02One choice

   Which part was hardest to understand?

   • Identity
   • Mechanism
   • Evidence
   • Testing
   • Regulatory context
   • Comparing sources
3. Q03Several choices

   Which format would help you learn?

   • Comparison
   • Case example
   • Short video
   • Long guide
   • Research methods

Observational documentation (health data) · 23

Would be used only within an approved study with consent and a protocol. Would allow “unknown”, “not applicable” or “prefer not to answer”.

1. Q04Coded outcome

   What outcome were you hoping to change?

2. Q05Relative timing

   When was the exposure chosen relative to any study invitation?

3. Q06Controlled identity list

   What exact product and molecule were recorded?

4. Q07One choice

   How certain is the identity?

   • Label only
   • Documentation available
   • Analytically characterized
   • Unknown
5. Q08Controlled route list

   Which formulation and route were documented?

6. Q09One choice

   Was this one ingredient, separate coadministration or a fixed mixture?

   • Single ingredient
   • Separate coadministration
   • Fixed mixture
   • Unknown
7. Q10Restricted study field

   What amount, unit and denominator were actually recorded?

8. Q11Structured timeline

   What schedule and exposure changes were recorded?

9. Q12Protocol-defined measure

   What baseline symptom or functional measure was available?

10. Q13One choice

    Was the baseline measured prospectively or recalled later?

    • Measured prospectively
    • Recalled later
    • Extracted from a record
    • Unknown
11. Q14Restricted study field

    What other medicines or products were used during the same period?

12. Q15Structured list of changes

    What changed in rehabilitation, training, nutrition or sleep?

13. Q16Protocol-defined measure

    Which outcome was measured at follow-up and by what method?

14. Q17One choice

    Was the outcome improved, unchanged, worse or unavailable?

    • Improved
    • Unchanged
    • Worse
    • Unavailable
    • Not comparable
15. Q18One choice

    Were there new symptoms or adverse events?

    • Yes
    • None reported
    • Unknown
    • Not assessed
16. Q19Relative event timeline

    When did the event begin relative to exposure and other changes?

17. Q20Restricted study field

    Was medical care obtained and what was the outcome?

18. Q21Coded reason

    Was the product stopped or changed, and why?

19. Q22One choice

    Why is follow-up missing, if known?

    • Not yet due
    • Declined
    • Unreachable
    • Withdrawn
    • Technical
    • Unknown
    • Other protocol code
20. Q23One choice

    Who supplied each observation?

    • Participant report
    • Clinician record
    • Laboratory record
    • Other document
    • Unknown
21. Q24Coded declaration

    Was a relevant financial relationship declared?

22. Q25Recorded by the system

    Which consent and protocol versions apply?

23. Q26Append-only audit

    Which fields were corrected and what was the reason?

How a record would be interpreted

Two fixed fictional records. They are not real people or survey results.