PNC-27 is an experimental peptide with reported anticancer activity in cell studies and mouse leukemia models. These findings do not establish effectiveness or safety in people, or a validated human dosing regimen. Selectivity depends on the experimental system and should not be interpreted as proof that normal human tissues are spared. Scientific/expert review pending.
Do not reuse those numbers or present a community cancer protocol as validated treatment. The error cannot be repaired by guessing what the author intended.
Sources and proposed-mechanism explanation
Cancer-cell membrane mechanisms are offered as the rationale. Selectivity in experimental systems is not demonstrated clinical cancer control.
- PNC-27 HDM-2 cell study, 2010 (new tab)
- FDA: illegal cancer products and PNC-27 contamination (new tab)
- Chondroitin sulfate as a molecular portal that preferentially mediates the apoptotic killing of tumor cells by penetratin-directed mitochondria-disrupting peptides. (new tab)
- Targeting cell membrane HDM2: A novel therapeutic approach for acute myeloid leukemia. (new tab)